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	Provedor de dados BJMBR (2) Autor Abreu,G.R. (1) Alho,C.S. (1) Bissoli,N.S. (1) Borgo,M.V. (1) Gouvêa,S.A. (1) Iturry-Yamamoto,G.R. (1) Lopes,A.B. (1) Moriguchi,E.H. (1) Moyses,M.R. (1) Romero,W.G. (1) Zago,A.C. (1) Zago,A.J. (1) Mais... Palavra-chave Coronary (2) Estrogen (1) Gene (1) Hypertension (1) Menopause (1) Nitric oxide synthase (1) Polymorphism (1) Tamoxifen (1) Unstable angina (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2011 (1) 2007 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Association of the 894G>T polymorphism of the endothelial constitutive nitric oxide synthase gene with unstable angina BJMBR Iturry-Yamamoto,G.R.; Moriguchi,E.H.; Zago,A.C.; Alho,C.S.; Zago,A.J.. The 894G>T polymorphism of the endothelial constitutive nitric oxide synthase gene consists of the substitution of a guanine base by a thymine at the 894th nucleotide of the gene. An association of this polymorphism with acute coronary syndromes has been described, only when in combination with other polymorphisms of this gene. The aim of the present study was to search for an association between this polymorphism and unstable angina in a southern Brazilian population. In a case-control study, 156 patients (group 1 (N = 83): unstable angina, group 2 (N = 73): stable angina) were genotyped by PCR and digestion of the product. Univariate analysis demonstrated that the minimal luminal diameter and the degree of stenosis of the culprit lesion differed... Tipo: Info:eu-repo/semantics/article Palavras-chave: Nitric oxide synthase; Gene; Polymorphism; Unstable angina; Coronary. Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000400005 Effect of tamoxifen on the coronary vascular reactivity of spontaneously hypertensive female rats BJMBR Borgo,M.V.; Lopes,A.B.; Gouvêa,S.A.; Romero,W.G.; Moyses,M.R.; Bissoli,N.S.; Abreu,G.R.. Tamoxifen has been associated with a reduction in the incidence of myocardial infarction. However, the effects of tamoxifen on coronary reactivity have not been fully elucidated. The objective of this study was to determine the effects of chronic treatment with tamoxifen on coronary vascular reactivity in spontaneously hypertensive rats (SHR). Female SHR were divided into four groups (N = 7 each): sham-operated (SHAM), sham-operated and treated with tamoxifen (10 mg/kg) by gavage for 90 days (TAMOX), ovariectomized (OVX), and ovariectomized and treated with tamoxifen (OVX+TAMOX). Mean arterial pressure (MAP), heart rate (HR), coronary perfusion pressure (CPP), and coronary vascular reactivity were measured. MAP and HR were reduced (9.42 and 11.67%,... Tipo: Info:eu-repo/semantics/article Palavras-chave: Tamoxifen; Estrogen; Hypertension; Menopause; Coronary. Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000800008 Registros recuperados: 2 Primeira ... 1 ... Última

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